Viral haemorrhagic fever (VHF)
Viral haemorrhagic fever (VHF)
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Pathogens
Pathogens
All ss RNA virus
Ebola (Philo): incubation 3-21 days
Marburg (Philo):
Crimea Congo
Lassa
Clinical
Sudden onset
Lassa
Diagnosis
Diagnosis
Nucleic acid detection: RT-PCR, RT-LAMP, Recombinase polymerase amplification (RPA), Next Generation Sequencing (NGS) e.g. MinION
Treatment
Treatment
Filovirus: Ebola (Inmazeb, Ebanga, Ervebo), Marburg
Arenavirus (Lassa: ribavirin (Rib), Junin (Junin Candid #1 vaccine strain), Machupo (nil)
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