West Nile fever / encephalitis
West Nile fever / encephalitis
Pathogen
Pathogen
Epidemiology
Epidemiology
Blood transfusion
Clinical features
Clinical features
Incubation period 2-15 days
Most are self-limiting
Fever, headache
Dengue-like: Muscle pain, rash, lymphadenopathy
Sometimes: encephalitis... , parkinsons syndr, polio-like illness
Rarely, pancreatitis, hepatitis
Diagnosis
Diagnosis
Clinical signs...
Virus isolation: CSF sample, brain
Nucleic acid: RT-PCR (but viraemia finished when encephalitis started)
Antibody (HI, IFA, CF, ELISA): IgM in serum or CSF
Treatment
Treatment
No specific treatment, supportive
Prevention
Prevention
History
History
Outbreaks in the USA in 2002 and 2003