Herpes Simplex Virus (HSV)
Herpes Simplex Virus (HSV)
Pathogen
Pathogen
Herpes simplex virus (usually type 2)
Epidemiology
Epidemiology
Common in all sexually active populations
Direct contact with genital secretions
Direct contact
Clinical features
Clinical features
Incubation period 2-7 days
Painful genital ulceration +/- vaginal d/c, malaise, LN
Lifelong infection, recurrences
Encephalitis
Neonatal
Vertical transmission - can be fatal
Diagnosis
Diagnosis
Culture
Serology
Nucleic acid detection: PCR of vesicle swab, blood, CSF
Treatment
Treatment
Aciclovir for 5-10 days